For a complete list of the 43 drugs that have bad side-effects when mixed with grapefruit, check here. To find out whether you need to keep grapefruit out of your diet, all you have to do is ask your doctor or pharmacist if the drugs you’re taking would react badly with grapefruit, says Graedon. But as new meds and new formulations make their way into your medicine cabinet, the number of drugs that you shouldn’t take with grapefruit has grown from 17 to 43-and this is in the past four years alone. More than 20 years ago, the same team of researchers that authored this current study discovered the dangerous interaction. But if you take it along with grapefruit or grapefruit juice, you might get the equivalent of three, four, or even 10 more pills, he says.Īnd this isn’t the first time grapefruit has been busted as a health hazard. So, for example, if you’re prescribed a specific dose of a blood pressure pill, that dose alone is meant to keep your blood pressure in check. “Because the drug isn’t metabolized the way it normally would be, you end up with a greater potential for toxicity,” he says. Grapefruit provides significant amounts of vitamins A and C and is relatively low in calories and low on the glycemic index, making it a nutritious fruit choice for diabetics. Seville oranges, used to make marmalade, and limes contain the same active ingredients that cause the drug problems. Weight gain is the result of consuming too many calories. Grapefruit is the biggest threat, but other fruits can interfere with drugs, too.
However, you can have too much of a good thing. This ingredient in grapefruit deactivates an enzyme in the stomach that breaks down drugs, which can cause the amount of the drug in your blood to go up, says Graedon. Grapefruit juice can help you lose weight and reduce your risk of type 2 diabetes, according to a study in the 'Journal of Medicinal Food' conducted by the Department of Nutrition and Metabolic Research at Scripps Clinic in California. The culprit behind all this trouble? Furanocoumarins.
For women, that could include birth control pills, some anti-anxiety drugs, and sleeping pills, according to Joe Graedon, MS, a pharmacologist and co-founder of the website. Many of the meds that have been found to be dangerous are completely necessary for treating important and common medical conditions, according to the study.
Turns out, eating grapefruit can cause serious-even life-threatening-side effects if you mix it with any of 43 drugs, according to a new study published in the Canadian Medical Association Journal. Filling up on grapefruit might help you drop a few pounds, but proceed with caution: It could be hazardous to your health.
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